Table 2

Probiotics in treatment of allergies

Author

Year

Study type

Probiotic type

Results


Giovannini

2007

R, PC, DB

L. casei DN-114001

Longertime free from asthmaIrhinitis episodes Less number of episodes of rhinitis episodes


Tamura

2007

R, PC, DB

L. casei strain shirota

No change in allergic rhinitis


Xiao

2007

R, PC, DB

B. Ion gum BBS36

Ameliorate Japanese cedar pollinosis


Brouwer

2006

R, PC, DB

L. rhamnosus I LGG

Lower SCORAD (no different from placebo)


Fälster-Holst

2006

R, PC, DB

L. rhamnosus GG

Lower SCORAD (no different from placebo)


Passeron

2006

R, PC, DB

L. rhamonosus Lcr35 and prebiotic

Decreased SCORAD


Sistek

2006

R, PC, DB

L. rhamnosus, B. lactis

Decreased SCORAD


Xiao

2006

R, PC, DB

B. Iongum BBS36

Ameliorate Japanese cedar pollinosis


Xiao

2006

R, PC, DB

B. Iongum BBS36

Ameliorate Japanese cedar pollinosis


Ciprandi

2005

C

Bacillus clausii spores

Decreased nasal symptoms


Ishida

2005

R, PC, DB

L. acidophil us L-92

Decreased nasal and ocular symptoms


Peng

2005

R, PC, DB

L. plantar um 33

Decreased perennial allergic rhinitis


Viljanen

2005

R, PC, DB

LGG or MIX

Decreased SCORAD


Weston

2005

R, PC, DB

L. ferment um

Decreased SCORAD


Rosenfeldt

2004

R, PC, DB

L. rhamnos us and L. re uteri

Decreased frequency of gastrointestinal symptoms and lactulose:mannitaol ratio


Wang

2004

R, PC, DB

L. paracasei

Decreased frequency and level of bother of allergic rhinitis


Hattori

2003

C

B. breve M-16V

Ameliorate cutaneous and allergic symptoms


Kirjavainen

2003

R, PC, DB

LGG

Decreased SCORAD


Rosenfeldt

2003

R, PC, DB

L. rhamnos us and L. re uteri

Decreased SCORAD


Helin

2002

R, PC, DB

LGG

No effect on birch pollen allergy


Isolauri

2000

R, PC, DB

B. lactis (Bb-12) or LGG

Decreased SCORAD


Majamaa

1997

R, PC, DB

LGG

Decreased SCORAD


Wheeler

1997

R, PC, DB

L. acidophil us

Increased IFN-and less eosinophilia


R = randomized, C = controlled, PC = placebo-controlled, DB = double-blinded, LGG = Lactobacillus GG, SCORAD = severity scoring of atopic dermatitis index

Michail Allergy, Asthma & Clinical Immunology 2009 5:5   doi:10.1186/1710-1492-5-5

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