Factor XII mutations, estrogen-dependent inherited angioedema, and related conditions
Division of Clinical Immunology and Allergy, Department of Medicine, University of Toronto, Toronto, Ontario, Canada
Allergy, Asthma & Clinical Immunology 2010, 6:16 doi:10.1186/1710-1492-6-16Published: 28 July 2010
The clinical, biochemical and genetic features of the conditions known as estrogen-dependent inherited angioedema, estrogen-associated angioedema, hereditary angioedema with normal C-1 inhibitor, type III angioedema, or factor XII angioedema are reviewed. Discussion emphasizes pathogenesis, diagnosis, and management.