Research

Skin prick testing in patients using beta-blockers: a retrospective analysis

Irene N Fung¹ and Harold L Kim^1,2*

• * Corresponding author: Harold L Kim hlkim_kw@yahoo.ca

Author Affiliations

¹ McMaster University, Hamilton, Ontario, Canada

² University of Western Ontario, London, Ontario, Canada

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Allergy, Asthma & Clinical Immunology 2010, 6:2 doi:10.1186/1710-1492-6-2

Published: 20 January 2010

Abstract

Rationale

The use of beta-blockers is a relative contraindication in allergen skin testing yet there is a paucity of literature on adverse events in this circumstance. We examined a population of skin tested patients on beta-blockers to look for any adverse effects.

Methods

Charts from 2004-2008 in a single allergy clinic were reviewed for any patients taking a beta-blocker when skin tested. Data was examined for skin test reactivity, type of skin test, concomitant asthma diagnosis, allergens tested, and adverse events.

Results

One hundred and ninety-one patients were taking beta-blockers when skin testing occurred. Seventy-two patients had positive skin tests. No tests resulted in an adverse event.

Conclusions

This data demonstrates the relative safety of administrating of skin prick tests to patients on beta-blocker treatment. Larger prospective studies are needed to substantiate the findings of this study.