Table 3 |
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|
Type |
Alternate name |
Examples |
Mediators |
|
|
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|
I |
Allergy (immediate) |
Atopy • — Anaphylaxis • — Asthma • — Allergic rhinitis • — Angioedema • — Food allergy |
IgE |
|
|
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|
II |
Cytotoxic, antibody-dependent |
Erythroblastosis fetalis • Goodpasture’s syndrome • Autoimmune anemias, thrombocytopenias |
IgG, IgM |
|
|
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|
III |
Immune complex disease |
Systemic lupus erythematosus • Serum sickness • Reactive arthritis • Arthrus reaction |
Aggregation of antigens IgG, IgM Complement proteins |
|
|
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|
IV |
Delayed-type hypersensitivity, cell-mediated, antibody-independent |
Contact dermatitis • Tuberculosis • Chronic transplant rejection |
T cells, monocytes, macrophages |
|
|
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|
Warrington et al. Allergy, Asthma & Clinical Immunology 2011 7(Suppl 1):S1 doi:10.1186/1710-1492-7-S1-S1 |
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