Table 4

Overview of the defining features of innate and adaptive immunity [1].

Innate immune system

Adaptive immune system


Cells

Hematopoietic cells:

• macrophages

• dendritic cells

• mast cells

• neutrophils

• basophils

• eosinophils

• NK cells

• T cells

• non-hematopoietic cells

• epithelial cells (skin, airways, gastrointestinal tract)

Hematopoietic cells:

• T cells

• B cells


Molecules

cytokines

• complement

• proteins and glycoprotein

antibodies (Ig)

• cytokines


Response time

immediate

delayed by hours to days


Immunologic memory

none: responses are the same with each exposure

responsiveness enhanced by repeated antigen exposure


Warrington et al. Allergy, Asthma & Clinical Immunology 2011 7(Suppl 1):S1   doi:10.1186/1710-1492-7-S1-S1

Open Data