Table 3

Risk factors for the development of drug allergy [15]

• Patient-related factors:

• Age: young/middle-aged adults > infants/elderly

• Gender: Women > men

• Genetic polymorphisms

• Viral infections: HIV, herpes viruses

• Previous reaction to the drug

• Drug-related factors:

• High molecular weight compounds and hapten-forming drugs are more immunogenic

• Route: topical > intravenous/intramuscular > oral

• Dose: frequent/prolonged > single dose

HIV: human immunodeficiency virus

Warrington and Silviu-Dan Allergy, Asthma & Clinical Immunology 2011 7(Suppl 1):S10   doi:10.1186/1710-1492-7-S1-S10