Allergy, Asthma & Clinical Immunology

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This article is part of the supplement: Practical guide for allergy and immunology in Canada

Open Access Highly Access Review

Eosinophilic esophagitis

Stuart Carr1* and Wade Watson2

  • * Corresponding author: Stuart Carr

Author Affiliations

1 University of Alberta, Division of Clinical Immunology & Allergy, Edmonton, Alberta, Canada

2 Dalhousie University, Division of Allergy, IWK Health Centre, Halifax, Nova Scotia, Canada

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Allergy, Asthma & Clinical Immunology 2011, 7(Suppl 1):S8 doi:10.1186/1710-1492-7-S1-S8

Published: 10 November 2011

Abstract

Eosinophilic esophagitis (EoE) is an atopic condition of the esophagus that has become increasingly recognized over the last decade. Diagnosis of the disorder is dependent on the patient’s clinical manifestations and histologic findings on esophageal mucosal biopsies. Patients with eosinophilic esophagitis should be referred to both an allergist and gastroenterologist for optimal management, which may include dietary modifications, pharmacologic agents such as corticosteroids, leukotriene modifiers and biologics as well as mechanical dilatation of the esophagus. The epidemiology, pathophysiology, diagnosis, treatment, and prognosis of EoE are discussed in this review.