Table 3 |
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|
Comparison of HAE and AAE. |
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|
Age of onset |
Family history |
Complement levels |
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|
|
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|
C1q |
C4 |
C1 inh level |
C1 inh function |
|||
|
|
||||||
|
HAE Type 1 Type 2 |
Early |
Yes* |
Normal Normal |
Low Low |
Low Normal/elevated |
Low Low |
|
|
||||||
|
AAE |
Late |
No |
Low |
Low |
Normal or low |
Low |
|
|
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|
*In approximately 25% of patients, no family history is identified; the disorder results from spontaneous mutation of the C1 inhibitor gene. C1 inh: C1 inhibitor |
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|
Kanani et al. Allergy, Asthma & Clinical Immunology 2011 7(Suppl 1):S9 doi:10.1186/1710-1492-7-S1-S9 |
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